New Delhi:Approval for human clinical trials for two made-in-India COVID-19 vaccine candidates - COVAXIN and ZyCov-D - marks the \"beginning of the end\" for the novel coronavirus pandemic that has infected over 1.12 crore people worldwide and left more than 5.3 lakh dead, the government said on Sunday.Striking an optimistic note, a letter by the Ministry of Science and Technology said there were more than 100 vaccine candidates in the world currently, of which 11 were in human trials.